Objective
To investigate the effects of a dietary fat reduction of about 10 % and a
concomitant change in simple (SCHO) and complex (CCHO) carbohydrates of
5 % leading to a change in the SCHO/CCHO ratio up to about 2/3 or 3/2, on
long term (6-18 months) food intake and body weight of overweight-to-obese
volunteers (BMI 26-34; average 30) with a habitual fat and carbohydrate
intake of 35-45 and 40-50 % respectively.
To investigate the acceptance of the proposed diets in various countries and
the effects of the dietary changes on well-being, body composition, energy
exchange, food habits, CHO and F metabolism, and on insulin response and
resistance of participants.
Concise description of the proposed content in each of the Countries DK, UK,
NL, DE, SP a group of 80 clinically healthy, free-living volunteers (40m, 40f;
age 20-55; BMI 26-34, average '30) will be randomly allocated to 2
experimental and 2 control groups, taking into account an equal distribution of
age, sex and BMI. Both experimental groups will have free and easy access
to fat-reduced food products (containing about 50 % fat compared with
normal products), to a variety of products with a high content of complex
CHO with a SCHO/CCHO ration of about 1/3 (exp. group f-CCHO) or to a
variety of products with a high content of simple CHO with a SCHO/CCHO
ratio of about 3/1 (exp. group f-SCHO). Food products will be provided via a
computer-controlled cafeteria system and will account for about 70 % of total
fat intake and 50 % of total CHO intake. In this way in both experimental
groups a reduction in total fat intake from #40 to #30 % and, in addition, in the f-CCHO and in the f-SCHO-group a SCHO/CCHO ration of up to about 2/3 and 3/2 respectively will be achieved.
One control group (cd) will have free access to a variety of products leading to a fat intake of #40 % and a CHO intake of #45 % with the for each country usual SCHO/CCHO ratio. The other control group (cs) only serves to observe (and to correct for) possible seasonal changes in body weight. The total experimental period will last 24 months : a) a preliminary period of 8 months to recruit volunteers, to set up and get acquainted with the food supply system and to determine the individual food habits of the participants with respect to fat and CHO intake; b) a dietary experimental period of 8 months in which food products will be available for the 2 experimental groups and 1 control group (cd); c) a period of 8 months in which long term effects on food habits, body composition and body weight after the dietary
experimental period will be investigated.
In the first and last period in each centre also specific effects of the proposed dietary changes on energy exchange, CHO metabolism and glucose tolerance will be studied. During the whole study anthropometry, food intake control and biochemical measurements will repeatedly be performed. The results will be presented in a workshop and exploited for industry and general public.
Fields of science
Call for proposal
Data not availableFunding Scheme
CSC - Cost-sharing contractsCoordinator
6200 MD MAASTRICHT
Netherlands