a) Demonstrate the significance of oxidative stress, and the role of the antioxidant systems in marine fish under highly controlled experimental conditions, primarily in weaned fish.
b) The characterization of the antioxidant system in marine fish during early development in order to understand and to enhance the growth and the quality of early life stages by avoiding oxidation problems that may cause pathologies and disease.
Development of rearing methods for marine fish larvae is still one of the major constraints for increasing aquaculture production of marine fish. Lipid peroxidation, specifically polyunsaturated fatty acid (PUFA) oxidation, is acknowledged as being highly deleterious resulting in damage to cellular biomembranes which contain large amounts of PUFA. Information in relation to in vivo lipid peroxidation and antioxidant defences either in wild or cultured fish species is quite limited.
To achieve the objectives the project will comprehensively investigate all three aspects involved in the control of lipid oxidation in marine fish, namely endogenous antioxidant systems, dietary inputs of highly unsaturated fatty acids (HUFA) and antioxidants, and lipid oxidation products.
Therefore, the project will determine, if possible, the PUFA status, antioxidant status and lipid oxidation status in fish from early stages to weaned fish in three marine species: gilthead sea bream, turbot and halibut.
The proposed work will increase knowledge of the biology of farmed European marine fish species with a view to improving larval quality and optimising their culture. If the project is able to demonstrate a beneficial effect of antioxidants, it could be a major step forward in the development of rearing methods for marine fish larvae.
Funding SchemeCSC - Cost-sharing contracts
FK9 4LA Stirling