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Content archived on 2024-05-14

Fish cysteine proteinase inhibitors and infectious diseases.

Objective

The objectives of this project are to isolate and characterize cysteine proteinase inhibitors in fish and study the role of these inhibitors in the defence against bacteria and viruses.

Enough primary structure of these inhibitors will be determined either by cloning or direct sequencing for comparison with the mammalian cysteine proteinase inhibitors. The effect and biological mechanism of fish cysteine proteinase inhibitors on apoptosis and other microbiological damage will be investigated. Interesting cysteine proteinase inhibitors will be cloned and expressed as recombinant proteins. The will then be purified and used in biological studies. To investigate the specificity of these inhibitors cysteine proteinases will be isolated. Our hypothesis is that this 'inhibitor system' is a novel non-specific defence system of organisms against infections.
The main goal of our proposal is to elucidate the effects of these proteins and possibly find ways of using the molecules as drugs in aquaculture industries.

Fields of science (EuroSciVoc)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

University of Tromso
EU contribution
No data
Address
Breivika
9037 Tromso
Norway

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

No data

Participants (4)

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