Objective
This project aims to :
1. provide a better understanding of bivalve-pathogen interactions
2. identify environmental factors, which modulate shellfish internal defence by using biological models developed by the partners
3. use the above information for prediction and management of the impact of disease on cultivated stocks.
As the stress generated by acute or long-term changes in environmental factors may have an effect on the interaction between hosts and pathogens in shellfish populations, the following fundamental questions will be addressed:
- Are the seasonal or occasional changes in infection or parasitism levels which are actually observed in cultured stocks related to measurable changes in host defence mechanisms?
- Which mechanisms in the defence process are targets for environmental immunosuppressors?
- Could the measurement of individual defence capacities become a tool for risk assessment and stock management?
METHODOLOGIES AND RESEARCH TASKS
Two models will be studied in parallel since previous work by the partners suggests that these models will provide important information on complementary steps in the pathogenic process. The bonamiosis model (Ostrea edulis / Bonamia ostreae = Oe/Bo) involves an internal parasite (Bo) and current investigations are focused on host (Oe) susceptibility and specificity at the cellular level. Vibriosis (Ruditapes philippinarum / Vibrio tapetis = Rp/Vt) is a true infectious disease clearly influenced by environmental factors and well adapted to epizootic monitoring. Each model provides an experimental system for investigation of a range of biological processes, from the overall susceptibility of individuals to immune cellular responses in hemolymph.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences health sciences infectious diseases
- natural sciences biological sciences biological behavioural sciences ethology biological interactions
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Programme(s)
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Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
29280 Plouzane
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.