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Content archived on 2024-05-24

Genetics of radiation induced cancer: identification and mapping of germline and somatic mutations determining predisposition

Objective

The project directly responds to the call to identify genes determining individual susceptibility to radiation-induced cancer. The experimental goals are to map and subsequently identify these genes. The benefits of this study will be the provision of individual risk assessments through genetic analysis, and a greater understanding of the biology of radiation carcinogenesis. The participants will conduct a series of animal experiments using the molecular genetic techniques of quantitative trait locus (QTL) mapping and loss of heterozygosity (LOH) analysis. Susceptibility to five common radiogenic tumour types affecting bone, gut, mammary, lung and lymphopoietic tissues will be studied. Through sharing of data with other consortia it is anticipated that a comprehensive set of genes determining susceptibility can be identified.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

GSF-RESEARCH CENTER FOR ENVIRONMENT AND HEALTH
EU contribution
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Address
Ingolstädter Landstrasse 1
85764 Neuherberg bei München
Germany

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (4)

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