Objective
Occupational exposure to radon in European uranium mines during the last 30 years was at low annual rate; follow-up of 10 000 miners over more than 20 years made it possible to organise a joint analysis. This joint study has a good statistical power, able to detect lom lung cancer risks linked to low annual exposure; modifying factors like attained age, dose-rate, and concomitant exposures (gamma, ore dust) will be studied in this large cohort. Nested case-control studies will be implemented in order to test the radon-tobacco interaction. Domestic radon plus occupational exposure will be studied in one of the case-control studies. Animal experiments will be continued. Mechanistic modelling will be applied to both animal and human data.
Programme(s)
Funding Scheme
CSC - Cost-sharing contracts
Coordinator
92262 Fontenay Aux Roses
France
Participants (7)
OX11 0RA Didcot,harwell,chilton
85764 Oberschleissheim
92265 Fontenay Aux Roses
85764 Oberschleissheim
3720 BA Bilthoven
100 00 Praha 10
OX11 0RQ Didcot