Quantification of lung cancer risk after low radon exposure and low exposure rate: synthesis from epidemiologic and experimental data

Project Information

UMINERS + ANIMAL DAT

Grant agreement ID: FIGH-CT-1999-00013

Project closed

Start date 1 February 2000

End date 1 August 2003

Funded under

• Research and training programme (Euratom) in the field of nuclear energy (1998 to 2002)

Total cost € 1 539 527,00

EU contribution € 795 332,00

Coordinated by

INSTITUT DE RADIOPROTECTION ET DE SURETE NUCLEAIRE
France

Objective

Occupational exposure to radon in European uranium mines during the last 30 years was at low annual rate; follow-up of 10 000 miners over more than 20 years made it possible to organise a joint analysis. This joint study has a good statistical power, able to detect lom lung cancer risks linked to low annual exposure; modifying factors like attained age, dose-rate, and concomitant exposures (gamma, ore dust) will be studied in this large cohort. Nested case-control studies will be implemented in order to test the radon-tobacco interaction. Domestic radon plus occupational exposure will be studied in one of the case-control studies. Animal experiments will be continued. Mechanistic modelling will be applied to both animal and human data.

Fields of science

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques.

• natural sciences › chemical sciences › inorganic chemistry › noble gases
• medical and health sciences › clinical medicine › oncology › lung cancer

Programme(s)

• FP5-EAECTP C - Research and training programme (Euratom) in the field of nuclear energy (1998 to 2002)

Topic(s)

• 2.1.3.-1.1. - Risk estimates for exposures at low dose and low dose rate

Call for proposal

Data not available

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

INSTITUT DE RADIOPROTECTION ET DE SURETE NUCLEAIRE

• EU contribution: No data
• Address: Rue Auguste Lemaire ; 92262 FONTENAY AUX ROSES ; France
• Total cost: No data

Participants (7)

AEA TECHNOLOGY PLC

United Kingdom

• EU contribution: No data
• Address: Harwell 551 ; OX11 0RA DIDCOT,HARWELL,CHILTON
• Total cost: No data

BUNDESAMT FUER STRAHLENSCHUTZ

Germany

• EU contribution: No data
• Address: 1,Ingolstädter Landstraße 1 ; 85764 OBERSCHLEISSHEIM
• Total cost: No data

COMMISSARIAT A L'ENERGIE ATOMIQUE

France

• EU contribution: No data
• Address: Avenue du General Leclerc 60-68 ; 92265 FONTENAY AUX ROSES
• Total cost: No data

GSF-RESEARCH CENTER FOR ENVIRONMENT AND HEALTH

Germany

• EU contribution: No data
• Address: Ingolstaedter Landstrasse 1 ; 85764 OBERSCHLEISSHEIM
• Total cost: No data

NATIONAL INSTITUTE OF PUBLIC HEALTH AND ENVIRONMENT

Netherlands

• EU contribution: No data
• Address: Anthonie van Leuwenhoeklaan 9 ; 3720 BA BILTHOVEN
• Total cost: No data

NATIONAL RADIATION PROTECTION INSTITUTE

Czechia

• EU contribution: No data
• Address: Srobarova 48 ; 100 00 PRAHA 10
• Total cost: No data

National Radiological Protection Board (NRPB)

United Kingdom

• EU contribution: No data
• Address: Chilton ; OX11 0RQ Didcot
• Total cost: No data