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Content archived on 2024-05-15

Quantification of lung cancer risk after low radon exposure and low exposure rate: synthesis from epidemiologic and experimental data

Objective

Occupational exposure to radon in European uranium mines during the last 30 years was at low annual rate; follow-up of 10 000 miners over more than 20 years made it possible to organise a joint analysis. This joint study has a good statistical power, able to detect lom lung cancer risks linked to low annual exposure; modifying factors like attained age, dose-rate, and concomitant exposures (gamma, ore dust) will be studied in this large cohort. Nested case-control studies will be implemented in order to test the radon-tobacco interaction. Domestic radon plus occupational exposure will be studied in one of the case-control studies. Animal experiments will be continued. Mechanistic modelling will be applied to both animal and human data.

Call for proposal

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Coordinator

INSTITUT DE RADIOPROTECTION ET DE SURETE NUCLEAIRE
EU contribution
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Address
Rue Auguste Lemaire
92262 FONTENAY AUX ROSES
France

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Participants (7)