Objective
Occupational exposure to radon in European uranium mines during the last 30 years was at low annual rate; follow-up of 10 000 miners over more than 20 years made it possible to organise a joint analysis. This joint study has a good statistical power, able to detect lom lung cancer risks linked to low annual exposure; modifying factors like attained age, dose-rate, and concomitant exposures (gamma, ore dust) will be studied in this large cohort. Nested case-control studies will be implemented in order to test the radon-tobacco interaction. Domestic radon plus occupational exposure will be studied in one of the case-control studies. Animal experiments will be continued. Mechanistic modelling will be applied to both animal and human data.
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Programme(s)
Call for proposal
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CSC - Cost-sharing contractsCoordinator
92262 Fontenay Aux Roses
France
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Participants (7)
OX11 0RA Didcot,harwell,chilton
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85764 Oberschleissheim
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92265 Fontenay Aux Roses
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85764 Oberschleissheim
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3720 BA Bilthoven
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100 00 Praha 10
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OX11 0RQ Didcot
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