Objective
The main objective is risk analysis for low doses of ionising radiation using a biologically based cancer model. Important aspects are: the form of the dose-effect relationship at very low doses and the question whether it is linear, linear-quadratic or whether there is a threshold. The ultimate aim is the derivation of improved estimates of radiation risks for radiological protection.
The main task for the applicant will be to continue working with the two-mutation carcinogenesis (TMC) model, to advance the model and make it applicable for other data sets and cancer in other organs, to use suitable animal data to investigate mechanistic aspects of radiological effects and to investigate suitable epidemiological data for description and model testing.
The proposed research allows to consider and possibly implement new concepts such as an induction of cellular defence mechanisms and bystander effects. These important radiobiological phenomena could be included and tested within the framework of the TMC model.
The applicant works in the field of low dose research since more than 8 years and is currently involved with the EU project CEC .Contract FIGH-CT-1999-00005. His range of knowledge and expertise in the field of the proposed research is interesting to be incorporated into the TMC model.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences nuclear physics
- medical and health sciences clinical medicine oncology
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
3720 BA BILTHOVEN
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.