Objective The degree to which neuronal phenotype in the developing spinal cord is progressively restricted by environmental signals is poorly understood. I intend to investigate this problem by examining targeted deletions of the NK1 gene in mice. This gene has been implicated in a particular aspect of the neuronal development such as the dorsoventral patterning of the neural tube and axon guidance across the midline. Embryos will be analysed using immunochemical, in situ hybridisation and dye tracing techniques, and in vivo approaches will be complemented by in vitro analysis after pharmaco logycal manipulation using spinal cord explants in collagen gels and roller culture of postimplantation embryos. Fields of science natural sciencesbiological sciencesneurobiologymedical and health sciencesclinical medicineembryology Programme(s) FP4-TMR - Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998 Topic(s) 0302 - Post-doctoral research training grants TL11 - Neurosciences (inc. Psychology) Call for proposal Data not available Funding Scheme RGI - Research grants (individual fellowships) Coordinator University de Alicante Address C.de san vicente de raspeig s/n 03080 Alicante Spain See on map EU contribution € 0,00 Participants (1) Sort alphabetically Sort by EU Contribution Expand all Collapse all Not available Spain EU contribution € 0,00 Address See on map
