New approaches towards the synthesis of c-glycosides

Project Information

Grant agreement ID: FMBI950332

Project closed

Start date 9 January 1996

End date 8 January 1998

Funded under

• Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Total cost No data

EU contribution No data

Coordinated by

UNIVERSITÀ DEGLI STUDI DI FERRARA
Italy

Objective

Saccharides in which the anomeric oxygen of the glycosidic bond is replaced by a carbon atom, the so-called 'C-glycosides', are an interesting class of carbohydrate antimetabolites. For instance, they are valuable tools in studying the role of carbohydrates in biological processes. Apart from this, they are possible enzyme inhibitors and a source of chiral synthons for the preparation of naturally occurring biomolecules. The main goal of this project is the development of a new, flexible methodology towards the stereoselective construction of C-glycosides, in which the two aldose are joined directly by carbon-carbon bonds. Therefore, we suggest an asymmetric hetero Diels-Alder approach for the construction of this class of C-glycosides.

Fields of science

• natural sciences › biological sciences › biochemistry › biomolecules › carbohydrates
• natural sciences › biological sciences › biochemistry › biomolecules › proteins › enzymes

Programme(s)

• FP4-TMR - Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Topic(s)

• 0302 - Post-doctoral research training grants
• TC01 - Synthesis, New Molecules and Methods

Call for proposal

Data not available

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

UNIVERSITÀ DEGLI STUDI DI FERRARA

• EU contribution: No data
• Address: Via Luigi Borsari 46 ; 44100 FERRARA ; Italy
• Total cost: No data

Participants (1)

Not available

Netherlands

• EU contribution: No data
• Total cost: No data