Objective
Amipurimycin and Miharamycins are nucleoside antibiotics active against Pyricularia oryzae, the phytopathogenic fungi causing the rice blast disease. (display: AMIPURIMYCIN MIHARAMYCIN A: X=OH MIHARAMYCIN B: X=H) These compounds exhibit the following common structural features: * Same 2-amino purine aglycon * Closely related branched chain moieties * C-glycopyranosylated alpha-aminoacid substructures including 6-amino-6-deoxy-hepturonic acids. The third point appears of particular importance owing to the fact that the absolute configurations at C-6' remain to be established. The present project is aimed at the syntheses of novel nucleosides containing these 6-amino-6-deoxy hepturonicacid moiety as well as the 2-aminopurine base. These compounds will be evaluated against Pyricularia oryzae in order to determinate the structural features responsible for the biological activity. All the new compounds will be submitted to phytobiologic studies in the Centre de tests Rhtne Poulenc Agrochimie.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology mycology
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs antibiotics
- agricultural sciences agriculture, forestry, and fisheries agriculture grains and oilseeds cereals
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
75005 Paris
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.