Objective
Olive pollen is considered to be one of the major causes of respiratory allergy in Mediterranean areas. Recent research has identified and purified major olive allergens at the biochemical level and several programmes have already been initiated in order to determine the ultrastructural localization as well as to clone olive allergens.
During the tenure of the grant it is intended to determine the distribution of allergens and allergen-coding mRNAs in different olive tissues and at different stages of development. The method will be based on in vitro translation of mRNAs extracted from the tissues to be tested. The translated proteins will be analysed by SDS-PAGE, transferred to membranes and probed using a variety of sera and MAb to allergens.
The goal of the project is to analyse the spatial and temporal replatio of the expression of allergen genes, a crucial step towards understanding their function and their eventual manipulation. New data about cross-reaction between allergenic proteins in different species are also expected.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- medical and health sciences clinical medicine allergology
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Programme(s)
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Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
18080 Granada
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.