Objective
Resistance in tomato against the fungal pathogen Alternaria alternata f. sp. lycopersicon is conferred by a single semi dominant locus called Asc . The locus was positioned between two closely linked Restriction Fragment Length Polymorphism (RFLP) markers, thus allowing to clone the Asc gene(s) by a map based strategy. A contig of Yeast Artificial Chromosomes (YACs) was obtained, providing closer markers around the Asc locus. The position of the Asc locus was delimited to a 200 kb fragment. As a first step, the Asc gene(s) will be cloned into cosmids obtained from the YAC containing the Asc locus. The corresponding genomic and the cDNA fragment(s) will be sequenced, giving access to the structure of the gene(s). As a second step, by performing experiments on gene expression and regulation and by studying gene homologues in other species, the Asc gene(s) function will be determined in relation to the disease resistance.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology mycology
- natural sciences biological sciences genetics chromosomes
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Programme(s)
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Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
1081 HV Amsterdam
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.