Objective
SRP-mediated targeting of membrane proteins
The aim of the project is to investigate the role of the signal recognizing particle (SRP) and FtsY, the E. coli homologues of the eucaryotic SRP and docking protein, respectively, in the targeting of membrane proteins to the cytoplasmic membrane of E. coli. Until recently, research on the targeting and assembly of membrane proteins in the cytoplasmic membrane of E. coli has completely focussed on the so-called general secretory pathway (GSP) which involves the sec-proteins. It has become clear that not all membrane proteins or domains thereof require the sec-machinery to insert properly into the cytoplasmic membrane of E. coli. This strongly points to the existence of more than one targeting mechanism for membrane proteins. Preliminary evidence strongly suggests that the SRP and FtsY are involved in the targeting of membrane proteins to the cytoplasmic membrane of E. coli.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
106 91 Stockholm
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.