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Modelling of the interactions between respiration and cardiovascular variabilities and their regulation by the autonomic nervous system

Objective



In the previous project we investigated the coupling between respiration and heart rate and blood pressure and their regulation by the autonomic nervous system (ANS). Different signal processing tools (LARY_C and modified complex demodulation) have been developed to analyse these interactions and their relation with the ANS. Starting with this knowledge, we want to develop a model for this short term regulation of the cardiovascular system, with emphasis on the influence of the respiration on the whole system. Such a model has to be able to fit to real data, producing parameters significantly modified in different physiological situations (changes in respiration rate and volume, pharmacological blockade of the ANS) and to reveal in an early stage some ANS related diseases.

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

Institut National de Recherche en Informatique et en Automatique - INRIA
Address
Domaine De Voluceau-rocquencourt
78153 Le Chesnay
France

Participants (1)

Not available
Belgium