Objective
1) Training in the methodology of antifungal susceptibility testing. The applicant would be taught how to perform in vitro susceptibility testing of Candida species. The applicant will assess in vitro the activity of a novel antifungal compound in collaboration with an industrial partner and participate in work on the validation of in vitro susceptibility testing in the clinical setting.
2) Training in real-time imaging microfluorimetry. The applicant will learn how to study changes in intracellular pH and [Ca2+] using imaging microfluorimetry. He will determine whether azole resistant isolates of Candida exposed to an azole show a more profound rise in intracellular pH or calcium compared with azole susceptible isolates. Furthermore, he will examine the pHi and Ca2+ changes in pairs of susceptible and resistant clinical isolates to fluconazole.
3) Training in azole antifungal population pharmacokinetics. Using a population pharmacokinetics approach, the applicant will determine whether late stage AIDS patients have equivalent serum concentrations of fluconazole as those with higher CD4 counts. Serum concentrations will be measured by bioassay and the applicant would learn this simple procedure.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences inorganic chemistry alkaline earth metals
- medical and health sciences health sciences infectious diseases RNA viruses HIV
- medical and health sciences basic medicine pharmacology and pharmacy pharmacokinetics
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
M13 9WL MANCHESTER
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.