Objective
Fluorescence resonance energy transfer (FRET) techniques offer a new and unique approach for evaluating molecular interactions within cells, and have led to breakthroughs in our understanding of DNA structures. The objective of the proposed research is to extend the current FRET techniques to offer the capability for continuous observation at a high temporal resolution. The innovative aspect of the method described in this proposal is that it will minimize the probability of irreversible destruction of the donor or acceptor, which cannot be achieved with the current photobleaching FRET techniques.
The proposed concept will be implemented on a confocal microscope imaging system allowing the mapping of energy transfer efficiencies on a pixel-by-pixel basis. The method will be used to study nucleic acid interactions, and protein-nucleic-acid interactions in an
interdisciplinary effort with other scientists in the host laboratory.
Fields of science (EuroSciVoc)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
37077 Göttingen - Nikolausberg
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.