Biodegradable polyalkenoate cements

Project Information

Grant agreement ID: FMBI961390

Start date

End date

Funded under

• Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Total cost € 0,00

EU contribution No data

Coordinated by

University of Limerick
Ireland

Objective

The objective of this project is to look at the feasibility of developing a biodegradable bone glue for fracture fixation in orthopaedic surgery. Recently glass polyalkenoate cements formed from poly(acrylic acid) and ion leachable glasses have been developed as chemically adhesive bone cements. However there is a clinical need for a degradable adhesive. The objective of the current project is to synthesise and characterise poly(B Malic Acid). Poly(B Malic Acid) has the same chemical structure as poly(acrylic acid), but has an ester group in the polymer backbone and will hydrolyse to Malic Acid a metabolite of the TCA cycle. The chemistry of cement formation between Poly(B Malic Acid) anci ion leachable fluorosilicate glasse subsequently will be investigated and te mechanical properties of suitable cements characterised.

Fields of science

• medical and health sciences › clinical medicine › surgery
• natural sciences › chemical sciences › polymer sciences
• engineering and technology › materials engineering

Programme(s)

• FP4-TMR - Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Topic(s)

• 0302 - Post-doctoral research training grants

Call for proposal

Data not available

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

University of Limerick

• EU contribution: No data
• Address: Plassey Technological Park ; 61 Limerick ; Ireland
• Total cost: No data