Objective
To analyse the natural variation at a disease resistance gene locus in Arabidopsis. The chromosome 4 locus specifying resistance to the Peronospora parasitica isolate Cala2 will be examined in a large number of host accessions. Resistance genes from two accessions will be sequenced and compared to determine the degree of sequence divergence that occurs between functional alleles. Additionalyy, the corresponding susceptibility loci will be sequenced and compared. Current evidence is that susceptibility is caused by loss of the gene, but non-functional structural homologues could exist in other accessions. The universality of this observation will be tested and the loci sequenced. Analysis of the deleted regions could reveal the cause of this genomic instability. Sequence analysis of non-functional homologues will reveal the structures that are essential for recognition of the Cala2 pathogen isolate. Finally, the project will reveal the current evolutionary state of this gene locus in 100 UK accessions of Arabidopsis and give clues as to its stability in natural plant populations. To become familiar with the techniques involved in the molecular and classical analysis of disease resistance genes. This will envable me to assess strategies for manipulating disease resistance in crop plants. All these skills be useful to me in my future research career in Greece.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- agricultural sciences agriculture, forestry, and fisheries agriculture
- natural sciences biological sciences genetics chromosomes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
TN25 5AH Ashford
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.