Objective
Research objectives and content
The formation of the anterior-posterior and dorsoventral axes in Drosophila depends on three crucial symmetry-breaking events during oogenesis, all of which involve the localisation of specific mRNAs. 1) One of the two pro-oocytes is determined to become the oocyte 2) The position of the oocyte determines posterior 3) The position of the oocyte nucleus and gurken mRNA determines dorsal. Mutants in the five spindle genes disrupt all three of these processes, with spindle-C mutants producing the strongest phenotypes. I aim to clone and characterise the spindle-C gene to determine what role it plays in these events. This research should increase our understanding of the molecular events that underlie the origin of polarity in Drosophila and the mechanisms of mRNA localisation. Training content (objective, benefit and expected impact)
I have chosen to work in the Wellcome/CRC Institute as it is one of the leading Institutes in the field of Developmental Biology in Europe, and is very well-equipped for the research I wish to perfom. I will be affiliated with the Department of Genetics, University of Cambridge, and will participate in its PhD. program. This grant will enable me to study for my PhD. in a highly stimulating and intellectual environment with the best facilities available. I will obtain a solid training in both Drosophila genetics and molecular biology, a combination one cannot find in Ireland. Links with industry / industrial relevance (22)
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- natural sciences biological sciences developmental biology
- natural sciences biological sciences molecular biology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
CB2 1QR Cambridge
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.