Sensory stimulation-related haemodynamic responses during waking, slow wave sleep and rapid eye movement sleep - a functional magnetic resonance study in humans

Project Information

Grant agreement ID: FMBI972025

Project closed

Start date 1 November 1997

End date 31 October 1999

Funded under

• Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Total cost No data

EU contribution No data

Coordinated by

Institute of Neurology
United Kingdom

Objective

Research objectives and content
The rationale of the project arises from the paradoxical effect observed during Rapid Eye Movement (REM) sleep in regard to sensory information processing. In REM there is a total lack of perceptual awareness in relation to sensory stimulation despite the fact that thalamocortical system is similarly activated during Waking (W) and REM. Since early components of Somatosensory Evoked Potentials (SEPs) are present but late components are abolished in REM, it appears that in this state sensory information does not reach the cortex so that there is not neural substrate for perceptual awareness. In order to understand at which level in the brain sensor) processing is affected during REM we intend to test the operative modes of the thalamocortical system by presenting multimodal sensory stimulation across different behavioral states.
FMRI techniques will be used to delineate the functional anatomy and connectivity that reflects different sensory information processing operating during W, Slow wave Sleep and REM.
Training content (objective, benefit and expected impact)
The two years period would include theoretical and practical training in functional Magnetic Resonance and functional data analysis. This acquired knowledge would allow the applicant to combine the potential of functional imaging with her previous research experience in sleep physiology and polygraphic recording techniques.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

• medical and health sciences › basic medicine › anatomy and morphology
• engineering and technology › electrical engineering, electronic engineering, information engineering › electronic engineering › sensors
• medical and health sciences › basic medicine › physiology
• natural sciences › computer and information sciences › data science › data processing

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Programme(s)

• FP4-TMR - Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Topic(s)

• 0302 - Post-doctoral research training grants
• TL09 - Physiology

Call for proposal

Data not available

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

Institute of Neurology

• EU contribution: No data
• Address: Queen Square ; WC1N 3BG London ; United Kingdom
• Total cost: No data

Participants (1)

Not available

Italy

• EU contribution: No data
• Total cost: No data