Objective
Research objectives ant content
Our recent finding indicate that CD40-CD40L represent an important NK cytotoxicity activation pathway. One of the objectives of this proposal is to investigate the possibility that CD40 can be expressed on tumor cells and whether it can be recognized by autologous NK cells. The second objective is to generate new monoclonal antibodies panel to NK cells (NKmAbs) able to tune NK cell programs not only related to cytotoxicity function but also cytokine production.
Training content (objective. benefit and expected impact)
The benefit for the proponent is to improve capability to develop new monoclonal antibodies, and strenghted his knowledge in tumor immunology. The expected impact is to make available, a complete reagent panel able to give selective tuning of NK function, moreover the importance of the CD40-CD40L activatory pathway will be determined in a tumor cell system. Links with industry / industrial relevance (22)
The project will be carried out in collaboration with the MABTECH AB (Stockholm), the specific NK mAbs can be patented.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
171 77 Stockholm
Sweden
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.