Objective
Research objectives and content
In angiosperms, first pollen mitosis is a key event in the differentiation of the male gametophyte which determines the correct development of the sperm cells necessary for double fertilization, and therefore for plant fertility. Futhermore, this asymmetric division provides a rare opportunity to study the cellular and molecular basis for the establishment of cell polarity in plants. The laboratory directed by Dr. David Twell (Botany Department, University of Leicester, UK), has isolated a large number of Arabidopsis gametophytic mutants affected in cell division at first pollen mitosis. Six of these mutants show an alteration of the symmetry of microspore division: the microspore divides more symmetrically instead of asymmetrically. This symmetric division is followed by an incomplete or absent generative cell differentiation, indicating that this differentiation is critically dependent upon asymmetric cell division. The principal aims of the proposed work are to establish in detail the developmental profile of two of these Arabidopsis gametophytic mutants using cytological (confocal and electron microscopy) and genetic (crosses with mutant and transgenic lines) approaches (duration: 12 months), and to clone by transposon tagging the gene(s) responsible for these specific mutant phenotypes (duration: 24 months).
Training content (objective, benefit and expected impact)
The results may be of direct benefit in understanding fundamental developmental events in plants and animals which involve the establishment of cell polarity.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences optics microscopy electron microscopy
- social sciences sociology demography fertility
- natural sciences biological sciences cell biology cell polarity
- medical and health sciences basic medicine physiology cytology
- natural sciences biological sciences botany
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
LE1 7RH Leicester
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.