Objective
Research objectives and content
The scientific objective of this progamme is to gain insight into the mechanisms that control the transcriptional regulation of stem cell commitment and differentiation through the molecular and cellular analysis of single haematopoietic cells isolated from different stages of differentiation and ontogeny. My results will be of significant interest to researchers working on the basic biology of stem cells, as well as their use in transplantation and/or gene therapy. Since constitutive dysregulation of the balance between self-renewal and differentiation is an essential feature of the cancer process, this work also has implications for oncology.
Training content (objective, benefit and expected impact)
I will be exposed to state of the art molecular approaches for the analysis of single cells and intellectually benefit from joining and interacting with a centre which has a depth of interest in haemopoiesis, stem cell biology and leukaemia.
Links with industry / industrial relevance (22)
The group has no formal links with industry but their research has implications in this direction: a knowledge of stem cell biology is crucial to the rational development of anticancer therapies and the success of gene therapy in haematopoietic systems.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences medical biotechnology genetic engineering gene therapy
- natural sciences biological sciences cell biology
- medical and health sciences medical biotechnology cells technologies stem cells
- medical and health sciences clinical medicine transplantation
- medical and health sciences clinical medicine oncology leukemia
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
SW3 6JB LONDON
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.