Objective
Research objectives and content
Plasmodia are mosquito-borne protozoa which cause malaria. For successful transmission, the protozoa must evade the mosquito immune response. Insect endoparasites (endoparasitoids) suppress the immune system, specifically the encapsulation response, of their insect hosts by utilising viruses and virus-like particles (VLPs). Plasmodia are also known to contain VLPs, exclusively during stages of its lifecycle which occur within the mosquito vector. Morphological, cytochemical and molecular characterisation will reveal the true nature of the VLPs within Plasmodium and provide the basis for the assessment of their role in immune evasion.
Training content (objective, benefit and expected impact)
Dr.Brey's research group at the Pasteur Institute, which is currently researching the molecular biology and biochemistry of encapsulation within the anopheline malaria vectors, provides a unique opportunity to carry out this proposal. In addition, the extensive expertise in microbiology at the Pasteur Institute, especially in the fields of electron microscopy and virology will give me an opportunity to learn new techniques and explore novel approaches to the study of the parasite-vector relationship. Collaboration with this research group would allow me to broaden the knowledge of vector-parasite interactions acquired as part of my PhD and explore novel mechanisms to combat malaria through the application of a challenging new approach.
Links with industry / industrial relevance (22)
Fields of science (EuroSciVoc)
- medical and health sciences health sciences infectious diseases malaria
- natural sciences biological sciences microbiology virology
- natural sciences biological sciences microbiology protozoology
- medical and health sciences basic medicine immunology
- natural sciences biological sciences zoology invertebrate zoology
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
75724 Paris
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.