Objective
Research objectives and content
U. maydis is a model organism for studies on plant pathogen fungi. The aim of this project is to characterise signalling pathways components that act in relation with Gpa3, a G alpha subunit of heterotrimeric G protein in U. maydis pathogenic development. Gpa3 controls the cAMP pathway which plays a fundamental function in pathogenicity. Gpa3 also regulates a second pathway involved in tumor formation. Two different screen will be used to isolate genes regulating Gpa3 or genes involved in the second pathway controlled by Gpa3: a two-hybrid screen with Gpa3 as a target and a genetic screen based on the phenotype of an overactivated Gpa3 allele. The genes identified in these screens will then be submitted to an extensive genetic and physiological analysis with the help of knock-out mutants to understand the regulation of the two pathways and the biological relevance of their coordination.
Training content (objective. benefit and expected impact)
This project will allow me to extend the knowledge and expertise I gained during my Ph.D. on signalling pathways and fungi to aspects of pathogenic development in fungi. Due to the growing interest of companies and of the academic field in fungal pathogens this will broaden my carrier oportunities for the future.
Links with industry / industrial relevance (22)
Prof. Kahmann's group is actively cooperating with Bayer in a genome project with the aim to develop new antifungal targets.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules proteins
- natural sciences biological sciences microbiology mycology
- natural sciences biological sciences genetics genomes
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
80638 MUENCHEN
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.