Studies towards the total synthesis of taxoids

Project Information

Grant agreement ID: FMBI983124

Project closed

Start date 12 October 1998

End date 11 October 1999

Funded under

• Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Total cost No data

EU contribution No data

Coordinated by

Centre National de la Recherche Scientifique (CNRS)
France

Objective

Research objectives and content
The overall objective of this proposal is to develop efficient synthetic routes that improve the practicality of the construction of taxoid analogues. Development of methods for the synthesis of such molecules formingthe basic structures of biologically active products, is an area of active investigation. The proposed pathway starts from
methylcyclopentenone and benzoic acid methylester, which are readily available bulk chemicals, and places emphasis on step efficiency, simplicity and environmental factors. Furthermore, it allows numerous structural changes to be made in a very limited number of steps. The appropriateness of the experimental approach and procedures of the proposed scheme appears sufficiently promising to warrant completion. I
Training content (objective, benefit and expected impact)
I will learn a great deal from this experience in terms of modern instrumental methods and laboratory techniques. Undoubtedly such an undertaking will allow me to reach a high level of knowledge and secure for me a job back in my country.
Links with industry / industrial relevance (22)
The Rhtne-Pounlec Rorer company is interested to screen synthetic intermediates for biological activities.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: https://op.europa.eu/en/web/eu-vocabularies/euroscivoc.

• natural sciences › chemical sciences › organic chemistry › organic acids

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Programme(s)

• FP4-TMR - Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998

Topic(s)

• 0301 - Post-graduate research training grants
• TC01 - Synthesis, New Molecules and Methods

Call for proposal

Data not available

Funding Scheme

RGI - Research grants (individual fellowships)

Coordinator

Centre National de la Recherche Scientifique (CNRS)

• EU contribution: No data
• Address: Avenue de la Terrasse ; 91198 Gif-sur-Yvette ; France
• Total cost: No data