Objective
Research objectives and content
The yeast Saccharomyces cerevisiae can be utilised as a convenient model system in salinity studies. Recently, a large number of spontaneous mutants have been obtained that suppress the salt sensitivity of a yeast strain disrupted in the gene which encodes an ATPase that acts as the major sodium extrusion pump of yeast cells. The very high frequency at which these mutations occur, suggests that many different genes mutate. These mutations could influence important determinants of salt tolerance, such as targets of sodium toxicity, regulatory systems of membrane transporters or the transporters themselves.In this project we will isolate and characterise the mutations suppressing the salt sensitivity and clone the corresponding genes. With this system we expect to pick up novel sodium targets or transporters in yeast. These novel genes not only can illuminate the critical steps involved in salt tolerance, but also can provide useful biotechnological tools to improve salt tolerance in crop plants.
Training content (objective, benefit and expected impact)
During his PhD research the applicant has gained large practical experience in plant molecular genetics. The requested training would extend the practical knowledge to yeast molecular genetics, applied to an important environmental stress factor, namely the salinity problem. This does not only involve training in new techniques but also demands a complementation of the theoretical knowledge from the plant model to the microbial model. This would create a greater potential for the future career of the applicant.
Links with industry / industrial relevance (22)
The salinity problem is an important factor limiting plant productivity. Identification of novel halotolerance genes will allow development of new biotechnological tools to improve salt tolerance in crop plants, which is an urgent need for the future of agriculture.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences molecular biology molecular genetics
- natural sciences chemical sciences inorganic chemistry alkali metals
- social sciences economics and business economics production economics productivity
- natural sciences biological sciences genetics mutation
- agricultural sciences agriculture, forestry, and fisheries agriculture
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
VALENCIA
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.