Skip to main content

THE CENTRAL ROLE of THE UBIQUITIN PROTEASOME SYSTEM IN REGULATORY PROCESSES INVOLVED in IMMUNOLOGICAL, INFLAMMATORY, ENDOCRINOLOGICAL AND MALIGNANT DISORDERS

Objective



The ubiquitin pathway plays a major role in regulated degradation of cellular proteins. It is involved in basic processes such as cell cycle educated scientists. During the four years of training, a comprehensive education will be provided via a three-stage program: the Network will hire regulation, tumour suppression, antigen presentation, regulation of young scientists immediately after their Ph.D. for a period of two years, apoptosis, and modulation of signal transduction.
they will receive state-of the-art training in a research project using The objectives of the proposed project are to further elucidate the advanced facilities. Thereafter, they will be working in cooperative ubiquitin proteasome protein degradation system and to dissect the role of research projects (between partners). In total, six to ten post-doctoral the system in antigen presentation, regulation of cell cycle and degradation of growth and transcriptional regulators. Subsequently, it fellows will be educated.
will be possible to
identify potential targets for designed drug development in biomedicine and pharmaceutics. |
The proposed Network brings together prominent European researchers in the field and will become a platform of international standard. Together the partners have at their disposal all modern facilities required for advanced biomedical research. Its composition and stature guarantees pioneering and innovative breakthroughs in the future. True collaboration and technology transfer are essential for their success.

Funding Scheme

NET - Research network contracts

Coordinator

Rijksuniversiteit Utrecht
Address
1,Yalelaan
3508 TD Utrecht
Netherlands

Participants (4)

Institut Pasteur
France
Address
25,Rue Du Docteur Roux
75724 Paris
KAROLINSKA INSTITUTE
Sweden
Address
13,Doktorsringen
171 77 Stockholm
RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG
Germany
Address
Im Neuenheimer Feld 282
69120 Heidelberg
Universität Stuttgart
Germany
Address
55,Pfaffenwaldring 55
70569 Stuttgart