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Innovative materials and technologies for a bio-engineered meniscus substitute

Objective

A great number of European are suffering from meniscus defects, which often cause persistent knee pain and may lead to osteoarthritis, knee joint instability and consequent deterioration of the quality of life of the patient. For years the standard treatment of a torn meniscus was complete resection but today orthopedic surgeons are very keen on new techniques for replacing or regenerating this tissue. Over the past years, efforts have been made to develop a suitable meniscus substitutes to replace the degenerated meniscus but no fully-suitable material/products exist to date. The main objective of the proposed research is closely emulate the structure of the natural meniscus by using state-of-the-art tissue engineering technologies and highly biointeractive materials. By using a problem solving approach, the Proposers will develop of a novel, bio-engineered, living meniscus reconstruction material composed of autologous cells grown on novel biodegradable and bioactive scaffold .

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

FIDIA ADVANCED BIOPOLYMERS SRL
Address
Via Ponte Della Fabbrica 3/B
35031 Abano Terme
Italy

Participants (6)

ISTITUTO ORTOPEDICO RIZZOLI
Italy
Address
Via Di Barbiano 1-10
40136 Bologna
NATIONAL RESEARCH COUNCIL OF ITALY
Italy
Address
Piazzale Aldo Moro 7
80125 Napoli
UNIVERSITAET BASEL
Switzerland
Address
Hebelstrasse 20
4031 Basel
UNIVERSITY OF EDINBURGH
United Kingdom
Address
Teviot Place
EH8 9AG Edinburgh
UNIVERSITY OF MANCHESTER
United Kingdom
Address
Oxford Road
M13 9PT Manchester
UNIVERSITY OF VIENNA
Austria
Address
Waehringer Guertel 18-20
1090 Wien