Objective
This EWORK is aimed to explore the present state of art of epidemiological data on reproductive and/or developmental toxicity of pesticides on humans, and to assess their validity in the light of correspondence with relevant experimental data. It will contribute to the understanding of presumed role of pesticides for the increase in human reproductive health impairment, reported by epidemiologists and clinicians from several European countries the last decade. Review will be performed of the experimental data on reproductive and developmental toxicity of pesticides to identify compounds with a high potency, using criteria such as: severity of effects, low or comparable to real environmental levels effective dose levels, reproductive toxicity at dose levels without other types of systemic toxicity, effects on several steps of reproductive cycle, single exposure vs. chronic exposure effects, irreversibility of the effects.
The EWORK will contribute to: -the evaluation of the current guidelines for reproductive/developmental testing and risk characterization, especially the necessity for inclusions tests for endocrine disruption and sensitive endpoints for evaluation of effects of low dose levels; to assess the need for testing of generic pesticides for reproductive/developmental toxicity; -the elaboration of more relevant epidemiological study design with a detailed assessment of specificity, magnitude and timing of exposure; considerations will be given to possible impurities of pesticides as a source of contradiction between the different studies; -the initiation of similar studies in the associated countries; the EWORK will outline the principal objectives and methodology for the collaboration in the field of reproductive/developmental toxicity of pesticides between EU Members and Associated countries with different patterns of application and presumably different exposure of the population.
ftp://ftp.cordis.lu/pub/improving/docs/HPCF-2000-00038-1.pdf(opens in new window)
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
Bulgaria
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.