In recent years, animal models have become crucial to the development of basic and therapy-oriented biomedical research and tremendous methodological and technological progress has been achieved in the field of the genetic engineering and phenotypic analyses of animal models of human pathologies.
Transgenic animals offer new opportunities to analyse the physiopathological consequences of defined molecular lesions, notably important to a better understanding of cancer, and of immune-mediated and age-related diseases, and to devise new therapeutic strategies. These animals constitute a new biological resource which should shed light on the basic mechanisms governing these diseases of considerable and rapidly growing socio-economic importance to European society.
There exists a strong, transdisciplinary need and a similar demand, in the academic and industrial settings, for scientists trained in the principles and practice of phenotypical analysis of animal models.
The present proposal for a series of 3 annual Eurolab Courses on animal models of human diseases will respectively address the practical issues related to animal models for research on cancer, on immune-mediated diseases and on age-related diseases. They will focus on new, cutting-edge techniques for the engineering of animal models and on the methods used to harvest and interpret the data they allow to collect.
This proposal for a series of 3 Eurolabs is presented in tandem with an application for 3 annual Euroconferences which will address the scientific, ethical and legal issues related to research with animal models as applied to cancer, immune-mediated diseases and age-related diseases.