Objective
The transplantation of cells, tissues and organs is a rapidly evolving field of scientific knowledge and medical practice worldwide. Clinical applications include haemopoietic malignancies, immuno-deficiencies and organ failure. Transplantation also holds strong therapeutic potential for many other chronic degenerative diseases. The extreme genetic diversity of the European populations (donors/recipients), the specificities of Europe's national Public Health systems, and the fact that the legal, ethical and societal issues posed by basic and clinical research/practice in this field vary throughout Europe, all confer unique characteristics to the practice of transplantation biology/medicine in Europe.
Transplantation biology/medicine is a complex, integrated field that requires a multidisciplinary approach to the genetics and the molecular/cellular immune mechanisms controlling graft acceptance and optimal long-term function. A full understanding of the immunogenetics and histocompatibility governing all reactivity is a prerequisite for optimal matching of donors and recipients.
Haemopoietic and organ transplantation, as well as the fields of cancer, autoimmune and inflammatory diseases, and allergy will benefit from innovative immuno-intervention (tolerance induction, immune deviation and suppression, specific vaccination and immuno-modulation) solidly founded on basic concepts and experimental research.
Despite excellent European basic research and transplant centres, to date no European forum for high-level training exists in this field. This proposal concerns the creation of a multidisciplinary forum for basic and clinical scientists working in the academic and industrial settings, at the junior and senior levels. It also intends to promote reflection, at the European level, on the ethical, legal, and societal and public health questions that are specific to transplantation in Europe.
This project should catalyse trans-European scientific cooperation and increase the level of European excellence in this field. It should lead to safer selection and optimal matching of donor and recipient, and to the development and validation of new therapeutic perspectives able to impact on cancer immunotherapy and immuno-intervention in autoimmunity and allergy. It has already drawn the pledged support of pharmaceutical and biotechnological partners.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences health sciences public health
- medical and health sciences health sciences inflammatory diseases
- medical and health sciences clinical medicine allergology
- medical and health sciences basic medicine immunology immunotherapy
- medical and health sciences clinical medicine transplantation
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
75010 PARIS
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.