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Content archived on 2024-05-15

Application of high cell density bioreactors to whey bioutilization - modelling and scale-up strategy

Objective

The objective of this project is the optimisation of the continuous fermentation of the deproteinized cheese whey in an airlift bioreactor (CALR) using a flocculating yeast strain at lab and pilot plant scale and the development of a suitable scale-up procedure for industrial application of fermentation.
The project consists of five work packages:
1. Fundamental investigation of the hydrodynamics and characterisation of all phases present in three- phase airlift bioreactor;
2. Development of a three-phase hydrodynamic model enabling the reliable prediction of the main hydrodynamic parameters in batch and continuous airlift bioreactors during the fermentation process;
3. Experimental verification of the hydrodynamic model on alcoholic fermentation of cheese whey permeate at lab-scale continuous airift biorector;
4. Development of a complete bioreactor model and proposal of a suitable scale-up strategy for the airlift bioreactor;
5. Implementation of whey fermentation at pilot plant-scale CALR. Verification of the scale-up strategy by means of a scale-down procedure.

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Topic(s)

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Call for proposal

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Coordinator

UNIVERSIDADE DO MINHO
EU contribution
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Address
Largo do Paço Campus de Gualtar
4710-057 BRAGA
Portugal

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Total cost
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