Effect of natural and induced mutants will be analyzed to identify genes and genes products responsible for decreased or increased Arabidopsis seeds vitality and longevity. There is no doubt that genetic factors contribute to longevity characteristics in seeds. However, variable environment conditions during seed development, and those operating at harvest and in storage, could mask or amplify basic genetic differences among species and cultivars. Many biochemical changes occur in deteriorating seeds, but it is presently difficult to discriminate between primary and secondary events. Following are suggested to be basic to deterioration in seeds: chromosome aberrations and damage to the DNA, changes in synthesis of RNA and protein, changes in hormones level and membrane alterations. Visiting scientist has good experience in biochemical analyses of genes products involved in seeds vitality and longevity including determination of hormones (IAA, ABA) level and membranes protein and lipid composition. On the other hand, host institution has good experience in selection of Arabidopsis plants with natural and induced variation, crossing of plants and co-segregation of molecular markers to map the relevant genes. Exchange of described above research knowledge and technology will be useful for identification of genes and genes products involved in Arabidopsis seed vitality and longevity. Arabidopsis system is perfect tool to investigate genetical and physiological factors determining natural and induced variation of seeds vitality and longevity .