Objective
Combined vaccines capable of conferring simultaneous immunity to different pathogens or diseases upon one single injection emerge as the most manageable solution to protect people. Although some combined vaccines have already been successfully developed, very little is known on the actual immunological interferences that might occur between two or more antigen specific immune responses simultaneously induced in vivo. Antigenic competition is very poorly documented in the literature as well as in clinical trial data. Understanding the mechanisms positively or negatively regulating the interactions between simultaneous antigen specific immune responses is critical for the development of efficient multivalent vaccines. We therefore propose to set up in vivo and in vitro models that will allow us to study the molecular basis of interferences between several immune responses. Formulation capable of reducing these antigenic competitions will be tested. The expertise of AVP in the field of combined vaccines is extensive and long-lived. Conducting such work in AVP research facilities is a unique opportunity that should lead to the success of this project. The following will be provided: expertise and equipment of the host research facilities, a continuous monitoring by a multi-disciplinary scientific proug and the stimulating environment of the second largest city of France which provides many opportunities of scientific interactions.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine immunology
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
69280 MARCY-L'ETOILE
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.