The European Molecular Biology Laboratory (EMBL) Grenoble Outstation collaborates closely with the European Synchrotron Radiation Facility (ESFR), the world's leading third generation source, in providing state-of-the-art synchrotron radiation facilities to European structural biologists. The intensity and high collimation of the ESRF beams is unparalleled permitting crystallographic data to be measured on weakly diffracting samples, notably micro-crystals and very large complexes that cannot be performed elsewhere.
The beamlines at the ESRF available for macromolecular crystallography, particulary protein crystallography, are a fourendstation macromolecular crystallography undulator beamline (ID 14 EH 1-4), a bending magnet (BM14) and undulator bemaline (ID29) optimised for MAD crystallographic experiments and a microfocus undulator beamline designed for microcrystals (ID 13). All beamlines are equipped with fast-readout CCD detectors. An important additional factor provided by the Grenoble Outstation is the combination on one site of active biochemical and molecular biololgy laboratories in close proximity to the best synchrotron radiation facilities, which are open to all LifeSciences users of ESRT. This provides the ideal environment for visitors whishing to collaborate on challenging structural biology problems, to prepare and characterise their samples and to be trained in the use of synchrotron facilities.
Details of the beamlines operated by the Joint EMBL-ESRF Structural Biology Group (JSBG) are available on: http://www.esrf.fr/expfacilities/jsbg/jsbgbeamlines.html.Details on how to obtain EU support for use of ESRF public beamlines are available on: http://www.embl-grenoble.fr (click on Access to ESRF beamlines). There are two deadlines per year for ESRF applications (March and September). Details about how to apply to use the UK-EMBL MAD bending magnet beamline are available on: http://www.embl-grenoble.fr (click on Access to Mad beamline BM14).Applications for BM14 beamtime are considered any time.
Stephen Cusack, Grenoble outstation, 6 rue Jules Horowitz, Grenoble 38042, P.O. BOX 156x, France