Objective
This training network addresses the secretory pathway in plants with a special focus on proteins, their interactions with each other and other biomolecules, and the potential of this pathway for biotechnology. The network partners provide non-overlapping expertise in methods to elucidate bio-molecular interactions, ranging from genetic approaches via co-localisation to specific protein-protein interactions using the most advanced protocols. The aims are
1) to understand receptor function and signal transduction controlling protein sorting and vesicle transport,
2) the identification of novel sorting receptors and sorting mechanisms that are likely to be unique to the plant kingdom,
3) the molecular characterisation of interactions between chaperones and their ligands.
4) To study a group of products of the secretory pathway within a set of specific model system, elucidate their step-wise biosynthesis and transport, and the way in which manipulation of: the pathway is possible to redirect these molecules or to prevent turnover.
5) The predicted spin-off from this work will firstly contribute to the fundamental insight into the secretory pathway of plants and, secondly, help to evaluate the potential of the secretory pathway for directed pathway engineering in order to maximise productivity in plants of heterologous proteins with high added value, such as human serum proteins, antibodies, or vaccines.
Within the framework of this research programme, we aim to set the stage for contained plant fermentations in bioreactors with the help of small-scale feasibility studies. We believe this programme will be instrumental in the development of high capacity and cost effective production systems combined with environmentally save procedures, which is currently an important issue to re-gain public acceptance of biotechnological applications for plant cells.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- engineering and technology environmental biotechnology bioremediation bioreactors
- natural sciences biological sciences biochemistry biomolecules proteins proteomics
- social sciences economics and business economics production economics productivity
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
- engineering and technology industrial biotechnology bioprocessing technologies fermentation
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
LS2 9JT Leeds
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.