Objective
The main objectives are as follows:
To provide suitable sensitive and specific diagnostic tools in order to assess control of human, porcine and bovine cysticercosis via diagnosis and drug treatment in selected ecological zones. Of particular importance will be the detection of neurocysticercosis in man.
Selected recombinant antigens will be assayed as potential vaccine candidates.
Expected Outcome
Taenia saginata and Taenia solium are responsible for public health problems in addition to creating financial losses to cattle and pig producers in endemic areas. This project is directed towards the improvement of the available methods for control through improved diagnosis and immunoprophylaxis. The project is a second phase to a two year INCO-DC STD-3 project, it will further develop and apply the technology and reagents developed in Phase 1 and those developed in this project to epidemiological and vaccination trials in a range of endemic countries and introduce work on the closely related T. saginata. It is possible to work on both species since they are so closely related that they contain many cross-reactive determinants and can be regarded as reciprocal models.
* To transfer established diagnostic procedures from Europe to participating developing countries.
* To apply existing diagnostic tools to epidemiological monitoring and where appropriate control studies in participating developing countries.
* To clone, express and evaluate potentially diagnostic and protective antigens from oncospheres and immature metacestodes.
* To establish panels of defined sera for primary screening and evaluation of potentially useful recombinant antigens, both diagnostic and protective.
* To develop recombinant parasite antigen based detection assays.
* To carry out vaccine trials in pigs and cattle using potentially protective recombinant antigens.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences health sciences public health epidemiology
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
- agricultural sciences animal and dairy science domestic animals animal husbandry
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
EH25 9RG ROSLIN
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.