Objective
* Retrospective study (1988-1995) to determine the different subtypes present in the regions, to identify their geographical distribution and possible alterations of the proportions in different population groups over the observation period.
* Consistency check, whether the current distribution of subtypes in AIDS patients in a specific region is comparable to the distribution of subtypes in this region seven years ago (at the approximate time of infection.)
Expected Outcome
* The distribution of subtypes in different geographical regions and in different population groups.
* A probable change of predominance of subtypes over the years, which gives an insight into differences in transmission efficacy.
* Detection of new strains from other parts of Africa to the Mbeya Region.
* Detection of new variants.
* Essential information for the preparation of vaccine campaigns in this region
* Differences between the distribution of subtypes at the time of conversion (5-7 years ago) and the present distribution. This could reveal possible differences in pathogenicity in the different strains.
* 1.200 Tanzanian and 900 Ugandan serum samples are tested by V3-serotyping ELISA by the African partners.
* 10% of the samples will be reanalysed as control group by LMU by V3-serotyping ELISA.
* Approx. 20% of the 2100 samples will be untypable by V3-loop ELISA. These will be referred to Europe and will by analysed by HMA (SMH) and sequencing (LMU).
* Consistency check whether the subtype distribution of 100 AIDS patients of the year 1995 is comparable with the distribution of 100 AIDS of the year.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- humanities history and archaeology history
- medical and health sciences health sciences public health epidemiology
- medical and health sciences health sciences infectious diseases RNA viruses HIV
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
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Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
80802 München
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.