Many methods are available for monitoring genetic damage induced. The A. Hollander Course will concentrate on the commonly measured biomarkers (chromosome aberrations; micronuclei; DNA), but others (p53 protein levels; metabolic genotypes) will also be addressed. Distinguished scientists from the fields of toxicology, molecular biology, cytogenesis and epidemiology will present and discuss the state-of-the-art knowledge and recent developments in human monitoring for biomarkers. Course will include both lectures and demonstrations. The organiser is planning to arrange the financial support to attract participants from ex-Eastern Block Countries. An enrolment of 30 students is planned. These students are expected to be primarily junior researchers and graduate students, although the course would also be open to the more senior investigator who wants to conduct regional dialogue and create the network in human monitoring.