Objective The project will determine using a variety of genetic tests, whether people living income regions of Kazakhstan contaminated by radioactivity or chemical products display higher genetic load than those living in uncontaminated regions. The tests to be carried on cultured blood lymphocytes cover a wide spectrum from unstable chromosome aberrations, sister chromatic exchanges, micronuclei, stable translocations (deter-monition by the FISH method), mutations of the p53 gene, to the determination of the adaptive response of reacting to a geotaxis insult and the intrinsic sensitivity of cells to a geotaxis agent. Information will also be collected on the exposure history of the persons studied, including the presence of potentially confounding factors and present levels of heavy metals, radioactive contamination, etc. It is hoped that these results can be correlated to the health status of the population and have predictive value Fields of science humanitieshistory and archaeologyhistorynatural sciencesbiological sciencesgeneticsmutationnatural sciencesbiological sciencesgeneticschromosomes Programme(s) FP5-INCO 2 - Programme for research, technological development and demonstration on "Confirming the international role of Community research,1998-2002" Topic(s) Data not available Call for proposal Data not available Funding Scheme CSC - Cost-sharing contracts Coordinator UNIVERSITE CATHOLIQUE DE LOUVAIN Address Avenue e. mounier 72 1200 Bruxelles Belgium See on map EU contribution No data Participants (3) Sort alphabetically Sort by EU Contribution Expand all Collapse all INSTITUTE OF GENERAL GENETICS AND CYTOLOGY - ACADEMY OF SCIENCES OF THE REPUBLIC OF KAZAKHSTAN Kazakhstan EU contribution € 0,00 Address Prospekt al-faraby 75 480060 Almaty See on map Other funding No data N.N. PETROV INSTITUTE OF ONCOLOGY Russia EU contribution € 0,00 Address Leningradskaya street 68, pesochny 2 197758 Sint petersburg See on map Other funding No data UNIVERSIDADE NOVA DE LISBOA Portugal EU contribution € 0,00 Address 93,rua da junqueira 93 1349-008 Lisboa See on map Other funding No data