Objective
The fight against infectious agents is focused to an efficient treatment of the diseases associated with infections and to the prevention of them. Regarding prevention, the most cost-effective strategy is vaccination. Classical vaccines have used microbe molecules such as cell invasion proteins, critical virulence factors on highly antigenic molecules. However, most of these vaccines have failed to achieve good protection against intracellular bacteria. The most putative reason resides in the ability of microbes to elude the immune response by evolving specific mechanisms to interfere with celldegradative routes (i.e. natural cell defences). Intracellular pathogens could share analogous strategies and compounds for this interference and their characterization will be critical for new and effective vaccines that confer protection against more than one pathogen. On this regard, we plan to design an innovative live, recombinant multi competent vaccine for brucellosis and tuberculosis. Our approach will try to identify and construct a vaccine including the microbe molecules responsible for interfering with cell derivative mechanisms (i.e. the phagosomal transport of lysosomal proteins).
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology bacteriology
- natural sciences biological sciences biochemistry biomolecules proteins
- medical and health sciences basic medicine immunology
- medical and health sciences clinical medicine pneumology tuberculosis
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Data not available
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
28049 MADRID
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.