Objective
Hydatidosis is a parasitose caused by the larval stage of the Cestod Echinococcus granulosus. It has a worldwide distribution and affects a large number of domestic and wild ungulates, and accidentally, humans. In hyper-endemic areas, particularly in countries of the Maghreb, hydatidosis causes serious economical and public health problems. We propose the development of a vaccine that could protect the dog, host of adult stage of the parasite and thus could interrupt the life cycle of the parasite. Two proteins located in the tegumental region of Echinococcus granulosus and which are potent immunogens during infections in the dog will be expressed as recombinant proteins in genetically modified Salmonellae. They will provide the basis of an orally administered vaccine. The protective potential of these constructions will be determined in hyper endemic areas against 2 strains of the parasite, on laboratory dogs, then on sheepdogs.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences health sciences public health
- agricultural sciences animal and dairy science domestic animals
- natural sciences biological sciences biochemistry biomolecules proteins
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs vaccines
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
69373 LYON
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.