Towards controlling antimicrobial use and resistance in low-income countries-an intervention study in latinamerica

Objective

Irrational use and bacterial resistance to antimicrobials are major public health problems amplified in low- income countries. The project will describe antimicrobial use and resistance in healthy children in urban and remote rural communities of Bolivia and Peru. Antimicrobial use will be analysed by means of household surveys with a triangulation of methods. Antimicrobial resistance will be analysed in commensal flora using a robust resistance screening method. Resistant bacteria will be investigated for genetic resistance mechanisms. Influencing factors including policy and non-human use will also be analysed. To improve the situation a community intervention package focusing on rational use of antimicrobials will be evaluated. It will be developed and implemented in collaboration with the local public and private health services on the basis of the generated results enforced by the national drug policy. The project will contribute to a more appropriate antimicrobial use and evidence based antimicrobial policy.

Fields of science

• medical and health sciences › health sciences › public health
• natural sciences › biological sciences › microbiology › bacteriology
• medical and health sciences › basic medicine › pharmacology and pharmacy › drug resistance › antibiotic resistance

Programme(s)

• FP5-INCO 2 - Programme for research, technological development and demonstration on "Confirming the international role of Community research,1998-2002"

Topic(s)

• 1.2.1.-1.4. - Research for development

Call for proposal

Data not available

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

UNIVERSITY OF FLORENCE

Address

Viale Morgagni 85
50134 Firenze
Italy

Participants (12)

ACCION INTERNACIONAL POR LA SALUD BOLIVIA

Bolivia

Address

Av. Abel Iturralde 1178 (Miraflores)
not availa La Paz

DISTRITO DE SALUD CORDILLERA

Bolivia

Address

Calle Sargento Macedo S/n
Camiri

HOSPITAL APOYO YURIMAGUAS

Peru

Address

Calle Progreso 305-307
Yurimaguas - Loreto

INSTITUTO NACIONAL DE LABORATORIOS DE SALUD

Bolivia

Address

Zubieta 1889 - Miraflores
La Paz

INSTITUTO NACIONAL DE SALUD

Peru

Address

Capac Yupanqui 1400
Lima 11

KAROLINSKA INSTITUTE

Sweden

Address

Norrbacka
171 76 Stockholm

MINISTERIO DE LA SALUD

Peru

Address

Av. M. Grau S/n
Moyobamba - San Martin

REFERENCIAL LABORATORY OF LORETO

Peru

Address

Garcia Saenz 332
Iquitos - Loreto

TEKO GUARANI

Bolivia

Address

Calle Sargento Macedo S/n
Camiri

UNIVERSIDAD PERUANA CAYETANO HEREDIA

Peru

Address

430,avda Honorio Delgado 430-urb. Ingeniera- Smp
31 Lima

UNIVERSIT DEGLI STUDI DI SIENA

Italy

Address

Via Bracci, 16
53100 Siena

UNIVERSITY OF FLORENCE

Italy

Address

Viale Morgagni 48
50134 Firenze