Smear-negative pulmonary tuberculosis (SNPTB) is a problem both for clinicians, and for tuberculosis programme managers. This research project approaches SNPTB from three different perspectives:
(1) the laboratory perspective, by testing the feasibility of more valid and efficient methods for quality assurance of smear-microscopy,
(2) the clinical perspective, by testing the clinical audit cycle as a method to improve the quality management of smear-negative tuberculosis suspects and the validity of diagnostic work up and
(3) the health services organisation perspective in relation to (de)centralisation of different elements of the diagnosis of smear-negative tuberculosis. This study will contrast high and low incidence, centralised and decentralised, urban and rural settings. HIV-related aspects will be examined. Special emphasis is given to the operationalisation and dissemination of study findings.
Funding SchemeCSC - Cost-sharing contracts
11300 La Habana
LS12 9PL Leeds