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A system approach to optimising diagnosis of smear-negative tuberculosis in high and low prevalence countries of south-america

Objective

Smear-negative pulmonary tuberculosis (SNPTB) is a problem both for clinicians, and for tuberculosis programme managers. This research project approaches SNPTB from three different perspectives:
(1) the laboratory perspective, by testing the feasibility of more valid and efficient methods for quality assurance of smear-microscopy,
(2) the clinical perspective, by testing the clinical audit cycle as a method to improve the quality management of smear-negative tuberculosis suspects and the validity of diagnostic work up and
(3) the health services organisation perspective in relation to (de)centralisation of different elements of the diagnosis of smear-negative tuberculosis. This study will contrast high and low incidence, centralised and decentralised, urban and rural settings. HIV-related aspects will be examined. Special emphasis is given to the operationalisation and dissemination of study findings.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

INSTITUTE OF TROPICAL MEDICINE PRINCE LEOPOLD
Address
Nationalestraat 155
2000 Anvers /Antwerpen
Belgium

Participants (4)

INSTITUTO DE MEDICINA TROPICAL "PEDRO KOURI"
Cuba
Address
Autopista Novia Del Mediodia Km 6 1/2, La Lisa
11300 La Habana
UNIVERSIDAD MAYOR DE SAN SIMON
Bolivia
Address
371,Avenida Aniceto Arce 371- Muyurina
10 Cochabamba
UNIVERSIDAD PERUANA CAYETANO HEREDIA
Peru
Address
Avda Honorio Delgado 430-Urb. Ingeniera- Smp
100 Lima
UNIVERSITY OF LEEDS
United Kingdom
Address
Clarendon Road 71-75
LS12 9PL Leeds