Objective
A series of random and alternating polyampholytes as well as polyampholyte "soaps" will be synthesized by free radical polymerisation from commercially available monomers. Electrochemical, hydrodynamic and conformational characteristics of polyampholytes in aqueous and aqueous-salt solution will be determined by modern technique. Amphoteric macromolecules will be modified by ionic surfactants and mixed micelles in order to tune the specific affinity of polyampholytes with respect to biomolecules and to realize the mechanism of "molecular recognition". Labelling of polyampholyte molecules by fluorescent tags will be performed to develop the fluorescence assay for polyampholyte-protein complexation. The main attention will be paid to interaction of polyampholytes with selected proteins and characterization of polyampholyte-protein complexes. Optimal conditions and appropriate polyampholytes will be selected to separate and purify the target biomolecules from their mixture. Several approaches to recycle polyampholytes will be developed.
Fields of science (EuroSciVoc)
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
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Coordinator
00014 Helsinki
Finland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.