New Polymer Systems for Bioseparation

Project Information

Grant agreement ID: INTAS-2000-00113

Project closed

Start date 1 August 2001

End date 31 July 2003

Funded under

• International Association for the promotion of cooperation with scientists from the independent states of the former Soviet Union (INTAS), 1993-

Total cost No data

EU contribution € 90 000,00

Coordinated by

University of Helsinki
Finland

Objective

A series of random and alternating polyampholytes as well as polyampholyte "soaps" will be synthesized by free radical polymerisation from commercially available monomers. Electrochemical, hydrodynamic and conformational characteristics of polyampholytes in aqueous and aqueous-salt solution will be determined by modern technique. Amphoteric macromolecules will be modified by ionic surfactants and mixed micelles in order to tune the specific affinity of polyampholytes with respect to biomolecules and to realize the mechanism of "molecular recognition". Labelling of polyampholyte molecules by fluorescent tags will be performed to develop the fluorescence assay for polyampholyte-protein complexation. The main attention will be paid to interaction of polyampholytes with selected proteins and characterization of polyampholyte-protein complexes. Optimal conditions and appropriate polyampholytes will be selected to separate and purify the target biomolecules from their mixture. Several approaches to recycle polyampholytes will be developed.

Programme(s)

• IC-INTAS - International Association for the promotion of cooperation with scientists from the independent states of the former Soviet Union (INTAS), 1993-

Topic(s)

• 3 - Chemistry
• OPEN - OPEN Call

Call for proposal

Data not available

Funding Scheme

Data not available

Coordinator

University of Helsinki

• EU contribution: No data
• Address: A. I. Virtasen aukio 1 ; 00014 Helsinki ; Finland
• Total cost: No data

Participants (8)

Fraunhofer-Institut für Angewandte Polymerforschung

Germany

• EU contribution: No data
• Address: Geiselbergstrasse 69 ; 14476 Golm
• Total cost: No data

Institute of Polymer Materials and Technology

Kazakhstan

• EU contribution: No data
• Address: Satpaev Str.18a ; 480013 Almaty
• Total cost: No data

Irkutsk Institute of Chemistry

Russia

• EU contribution: No data
• Address: Favorskogo Str.1 ; 664033 Irkutsk
• Total cost: No data

M.V. Lomonosov Moscow State University

Russia

• EU contribution: No data
• Address: Leninskie Gory V-254 ; 119899 Moscow
• Total cost: No data

Potsdam University

Germany

• EU contribution: No data
• Address: Karl-Liebknecht-Strasse 24-25, Haus 25 ; 14476 Golm
• Total cost: No data

Romanian Academy

Romania

• EU contribution: No data
• Address: Aleea Grigore Ghica Voda 41 A ; 6600 Iasi
• Total cost: No data

University of Ljubljana

Slovenia

• EU contribution: No data
• Address: Askerceva 5 ; 1001 Ljubljana
• Total cost: No data

Université Catholique de Louvain

Belgium

• EU contribution: No data
• Address: Place L.Pasteur 1 ; 1348 Louvain-la-Neuve
• Total cost: No data