Objective
In contrast to extracts of the Ginseng root the biological activities of individual Ginseng glycosides have not yet been studied sufficiently. The Panax Ginseng glycosides differ from each other by the type of aglycone and by the type, number and position of the carbohydrate moiety.
In this research project the synthesis of some ginsenosides and of their analogues and comparative studies of their bioactivities with the natural ginsenosides isolated from Panax Ginseng will be carried out. Betulafolienetriol, a tetracyclic dammarane triterpene isolated from birch leaves will be used as a relatively accessible starting material for chemical transformations leading either to ginsenosides, pseudoginsenosides or semisynthetic analogues. Isolation and purification of natural glycosides from Panax Ginseng roots will be carried out in order to investigate their specific activity. Cytotoxicity assays will be performed on several cell lines of marine or human origin.
Fields of science (EuroSciVoc)
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
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Coordinator
91198 Gif-sur-Yvette
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.