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MRI System Development Correcting Motion Artifacts for Cardiac and Brain Diagnostic Applications

Objective

A major disadvantage in MRI (Magnetic Resonance Imaging) is that high quality images require long scan periods compared with the periods of physiologic motions (respiration, cardiac motion, blood flow, patient's restlessness). These long periods cause artifacts in the reconstructed images that can prevent accurate diagnosis. Thus, motion effects are the most important limitations in MRI. The proposed project addresses the problem of motion artifacts correction in MR brain and cardiac imaging. Its development objectives on MRI system technology are:(a) correct motion artifacts that severely affect Brain and Cardiac MRI applications(b) improve diagnostic procedures by exploiting the proposed reconstruction process(c) integrate the proposed developments with existing health information systems(d) provide a concept demonstration of proposed developments.

OBJECTIVES
- Develop MRI systems for Brain and Cardiac medical applications;
- improve diagnostic procedures;
- integrate project with the existing health information systems;
- concept demonstration.

DESCRIPTION OF WORK
Image reconstruction of Neurofunctional and Cardiac Magnetic Resonance Data that can be adaptively corrected for motion artifacts will have tremendous impact on early diagnosis of acute stroke and cardiac diseases. Stroke and heart problems are leading causes of death in the western world and - even more important - is the primary cause of serious disability with tremendous social cost involved. Since this decade has shown the potential of MRI to establish early differential diagnosis in the acute stroke situation, and heart diseases, the diagnostic progress has been accompanied by an enormous progress in therapeutic possibilities over the recent two years. However, head motion of typically uncooperative patients and heart movement causes severe degradation of image quality and prevents diagnosis. The proposed development aims to address the above essential requirement to define and develop novel information-technologies that track and correct organ motion and patient's restless in medical Magnetic Resonance Imaging (MRI) applications. The goal is to improve the diagnostic value of brain and cardiac MR images in order to at least partly replace invasive procedures based on imaging modalities that may apply ionizing radiation in the examination and diagnosis of cardiac diseases. Furthermore, the proposed motion correction MRI technology will be implemented to medical diagnostic cardiac and brain MR imaging applications including restlessness of patients. The proposed signal-image processing to remove motion artifacts in MRI applications will undoubtedly advance the state of the art in MRI research and technology area.

Furthermore, the proposed developments in:
- real-time motion correction MR Image reconstruction algorithms;
- image and data fusion between MRI, CT/X-ray and Ultrasound Image outputs would allow for a full exploitation of the tissue identification diagnostic capabilities of the MRI technology.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

PHILIPS MEDICAL SYSTEMS NEDERLAND B.V.
Address
Veenpluis 4-6
5684 PC Best
Netherlands

Participants (8)

FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Germany
Address
Hansastrasse 27C
80686 Muenchen
INNOVATIVE MAGNETIC RESONANCE IMAGING SYSTEMS INC.
Canada
Address
268 Grosvenor Street
N6A 4V2 London, Ontario
LAWSON HEALTH RESEARCH INSTITUTE
Canada
Address
268 Grosvenor Street
N6A 4V2 London, Ontario
MULTI-MAGNETICS INCORPORATED
Canada
Address
268 Grosvenor Street
N6A 4V2 London, Ontario
ST. JOSEPH S HEALTH CARE LONDON
Canada
Address
268 Grosvenor Street
N6A 4V2 London, Ontario
STAEDTISCHE KLINIKEN OFFENBACH
Germany
Address
Starkenburgring 66
63069 Offenbach
UNIVERSITAETSKLINIKUM HAMBURG-EPPENDORF
Germany
Address
Martinistrasse 52
20246 Hamburg
UNIVERSITY OF TORONTO
Canada
Address
27, Cercle King's College
M5S 1A1 Toronto