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Content archived on 2024-04-16

CELL SURFACE PROPERTIES AND TUMOUR SPECIFIC ANTIGENS : ROLE OF METASTASIS AND HOST IMMUNE RESPONSE

Objective

The objective is to improve our knowledge of the tumour cell properties that influence the specific immune response of the host and also the ability of tumour cells to invade surrounding tissues and to metastasise. This should lead to the development of new treatment by increasing the specific host immune response and by inhibiting the invasive potential of tumour cells.

Central to this project is the obtention and storage of freshly collected tumour material and the development of permanent tumour cell lines on which both the cell surface properties relevant for metastasis and the tumour-specific antigens may then be studied in detail by all the participating centers. In a first step, the histology of the collected tumours will be restricted to melanomas, sarcomas, ovarian, breast and colon carcinomas. Tumour specimens, reagents and scientific knowledge will be exchanged. Patients with these types of tumours will be selected by the participating groups and attempts will be made by some of the group to establish permanent cell lines. These cell lines will then be sent back to all groups for specific studies of their invasion-related properties and of their immunogenecity to autologous T lymphocytes.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Programme(s)

Multi-annual funding programmes that define the EU’s priorities for research and innovation.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CON - Coordination of research actions

Coordinator

Ludwig Institute for Cancer Research
EU contribution
No data
Address
Avenue Hippocrate 74
1200 Brussels
Belgium

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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