Objective
Susceptibility genes and environmental factors contribute to the rising incidence of melanoma in Europe. Tumor associated antigens on melanomas can be recognized by immune effectors. These antigens are the focus of immunotherapy protocols. Information is lacking, however, concerning expression of tumour associated antigens and the activation status of immune effectors at initial stages of tumour suppressor gene in melanocytes. The concordant expression of a tumour associated antigen will allow monitoring of the activation status of antigen-specific lymphocytes during tumour progression. This information is essential for the design of tumour antigen vaccination and other therapeutic protocols. This project requires a pluridisciplinary effort by groups involved in
(i) development of models of oncogenesis by somatic genetics in mice;
(ii) identification of melanoma associated antigens in humans and;
(iii) monitoring activation or inactivation in vivo and targeting of immune effectors or antigen presenting cells.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- medical and health sciences clinical medicine oncology skin cancer melanoma
- medical and health sciences basic medicine immunology immunotherapy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
13288 MARSEILLE
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.